Metabolic Pathways of Biochemistry - Tryptophan Biosynthesis

	Tryptophan Biosynthesis
	The 3-D version of this pathway doesn't yet exist.


Overall Reaction for the Pathway
Chorismate + L-Glutamine + 5-Phosphoribosylpyrophosphate (PRPP) + Serine	`--->`	L-Tryptophan + L-Glutamate + Pyruvate + PP_i + 2 H₂O + CO₂ + D-Glyceraldehyde-3-Phosphate


	Chorismate

L-Gln

L-Glu, Pyruvate

Anthranilate synthase


	Anthranilate

5-P-Ribosyl-PP (PRPP)

PP_i

Anthranilate-phosphribosyl transferase


	N-(5'-Phosphoribosyl)-anthranilate

Phosphribosyl-anthranilate isomerase


	1-(O-Carboxyphenylamino)-1'-deoxyribulose-5'-phosphate

CO₂, H₂O

Indole 3-glycerol phosphate synthase


	Indole-3-glycerol phosphate

Serine

G-3-P, H₂O

Tryptophan synthase


	L-Tryptophan


	[The Metabolic Pathways of Biochemistry] - [Copyright © 1998 Karl J. Miller.]

Tryptophan Biosynthesis