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SEMINARS
The series hosts a seminar about twice a month on current research topics. The seminar often features an invited guest speaker and occasionally local faculty members, students or others affiliated with the department. The usual time of the seminar is 11:00 a.m. on Fridays. Professors Hosam Mahmoud (E-mail: hosam@gwu.edu) and Jonathan Stroud (E-mail: stroud@gwu.edu) are the Seminar Series Coordinators.

 

Seminars in Spring 2009

 

Upcoming Seminar:


Analysis of Cohort Studies with Multivariate, Partially Observed Disease Classification Data

Speaker: Nilanjan Chatterjee, Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institute of Health

Abstract:
Complex diseases, like cancer, can often be classified into subtypes using various pathological and molecular traits of the disease. In this article, we develop methods for analysis of disease incidence in cohort studies incorporating data on multiple disease traits using a two-stage semi-parametric Cox proportional hazard regression model that allows one to examine the heterogeneity in the effect of the covariates by the levels of the different disease traits. For inference in the presence of missing disease traits, we propose a generalization of an estimating-equation (EE) approach for handling missing cause of failure in competing-risk data. We prove asymptotic unbiasedness of such an EE method under general missing-at-random (MAR) assumption and propose a novel influence-function based sandwich variance estimator. The methods are illustrated using simulation study and a real data application involving the Cancer Prevention Study (CPS-II) nutrition cohort.

Time: Friday, April 17, 2009, 11:00-12:00 pm

Location: Monroe Hall, Room 113 (2115 G Street, NW, Washington, DC 20052)


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Foggy Bottom-GWU Metro Stop on the Orange and Blue Lines.
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