Metabolic Pathways of Biochemistry

	Shikimate Pathway
	The 3-D version of this pathway doesn't yet exist.


Overall Reaction for the Pathway
D-Erythrose-4-phosphate + 2 Phosphoenoylpyruvate + NAD⁺ + NADPH + ATP	`--->`	Chorismate + NADH + NADP⁺ + ADP + 4 P_i


D-Erythrose-4-Phosphate	+	Phosphoenoylpyruvate

H₂O

P_i

Enzyme Complex


	7-Phospho-2-dehydro-3-deoxy-D-arabinoheptulosonate

NAD⁺

NADH, H⁺, P_i

Co⁺⁺

3-Dehydroquinate synthase


	3-Dehydroquinate

H₂O

3-Dehydroquinate dehydratase


	3-Dehydroshikimate

NADPH, H⁺

NADP⁺

Shikimate dehydrogenase


	Shikimate

ATP

ADP

Mg⁺⁺

Shikimate kinase


	3-Phosphoshikimate

Phosphoenoylpyruvate

P_i

3-phosphoshikimate-1-carboxyvinyl transferase

(EPSP synthase)


	3-Phospho-5-enoylpyruvylshikimate

P_i

Chorismate synthase


	Chorismate


	[The Metabolic Pathways of Biochemistry] - [Copyright © 1998 Karl J. Miller.]

Shikimate Pathway